The main aim of our research was to develop a wound healing adhesive bandage formulation consisting of Curcuma longa (Turmeric) for the treatment of wound healing. Herbal Adhesive Bandages present in market were having Antiseptic property only and the present study aimed to design, develop. Herbal wound pad containing powdered herbal drug’s i.e. Curcuma longa (Turmeric) the plants have been reported in the literature as having good antimicrobial, anti-inflammatory activity. A wound healing herbal adhesive bandage formulation consisting of Curcuma longa (Turmeric) extracts was prepared. Microbiological studies were performed safety of materials used in the formulation. The developed bandage consisting of Curcuma longa (Turmeric) was found to be safe and effective for the treatment of wound healing activity.

In recent years, medicinal plants gain much attention to maintain human health because of its less side effect. The therapeutic properties of traditional plants depends on phytochemical metabolites. In present paper ultrasonic parameter of leaves extract of Jatropha Curcas in methanol and ethanol studied respectively. The variation of ultrasonic velocity and related parameter like viscosity, acoustic impedance, adiabatic compressibility, intermolecular free length, relaxation time, throw light upon the structural changes associated with molecular interaction in liquid mixture.

Herbal gels are used since many years. Gel is the semisolid dosage form of at least two constituents, consisting of a condensed mass enclosing and interpenetrated by a liquid. It has an easy application, easy removable property. It is widely accepted dosage form, and it has more patient compliance. Tridax procumbens is an anti-bacterial drug, it also has wound healing activity for such activity it has been used in traditional medicinal systems in India, the rural parts of country still has a wide use of this plant. When it comes to its use in combination with certain modern dosage forms, gel seems to be a good option. This article gives 2 formulations of herbal gel, which contains. Tridax procumbens aqueous extract, carbopol 940 as a base in combination with triethanolamine.

Solid material of dimensions less than 100 nanometers (nm), having the nanoscale structures distance between different phases that makes the material. The nanocomposites are used to make building blocks having dimensions in nanometer to create and design new materials with good and remarkable flexibility and improves physical property. Therefore the definition of the nanocomposites include colloidal porous media usually taken for the solid combination of nano dimensional phases and bulk properties which differ in properties due to structure and chemical dissimilarities. From the component materials, the mechanical, thermal, electrical, optical, electrochemical, catalytic properties will differ. Nanocomposites have been used in various fields like in food packaging, agriculture and food, health and medicines, producing structural components to weight ratio, making tumours easier to see and remove. Also, nanocomposites are available in various marketed preparations.

Coal tar creosote is rich in various organic compounds which are reported to be potentially carcinogenic and harmful. Among the various compounds the predominant ones are assorted polycyclic aromatic hydrocarbons, phenols and heterocycles. Hence biodegradation of these recalcitrant constituents to reduce the toxicity of this multicomponent liquid is a major focus of research in this study. Coal tar effluent collected from an industrial site in West Bengal was subjected to microbial degradation by selected strains of mostly gram-negative bacteria viz. Escherichia coli, Pseudomonas aeruginosa and Salmonella abony and a single gram-positive strain viz. Staphylococcus aureus. Reduction of the BOD5 value from 250 to 30 and significant increase in colony forming unit count indicated Staphylococcus aureus as the most suitable resistant strain for degrading the effluent. Further evaluation of the degrading capacity of this strain and minimum inhibitory concentration (MIC) was done individually with 16 compounds comprising of 6 aromatic hydrocarbons (viz. benzene, toluene, m-xylene, naphthalene, phenanthrene, flourene), 3 phenols (viz. phenol, o-cresol, 2, 4-dimethyl phenol), 5 nitrogen heterocycles (viz. indole, quinoline, isoquinoline, carbazole, acridine), aniline and 1-naphthylamine. Staphylococcus aureus was found to degrade most of the compounds in variable extent except phenols (viz. phenol, o-cresol, 2, 4-dimethyl phenol), indole, isoquinoline, carbazole and aniline. Most effective degradation was found in case of aromatic hydrocarbons, especially in benzene followed by naphthalene and phenanthrene. Among heterocyclic compounds acridine followed by quinoline recorded a significant microbial growth.

Current research is about formulating microspheres containing metronidazole for vaginal infections for local action in bioadhesive polymers will improves patient compliance as well as disperses the drug throughout the vaginal cavity. The microspheres were prepared by solvent evaporation technique by using various proportions of eudragit RS and eudragit RL polymers. The microspheres were characterised for various parameters like FT-IR, DSC, % yield, entrapment efficiency, particle size determination, dissolution of microspheres and SEM, compatible. The % yield of microspheres ranged from 83.15 and 92.78. The encapsulation efficiency of metronidazole was in the range 63.82 to 72.26. The size of the microspheres ranged between 194 to 674μm. The microsphere formulation and microsphere loaded gel formulation follows Higuchi rule. The stability studies of microspheres was conducted at 4°C to 8°C and room temperature.

Pharmacy practice and the proficient roles of the community pharmacists particularly have sophisticated seriously from measly dispensing of pharmaceuticals to cognitive roles which are patient related. Cognitive pharmaceutical services are strategies and initiatives that perk up the worth of drug treatment and the health care delivery system with pharmacists to the entire scope of their preparation and learning as medication experts. Such shifting roles established at developed countries in the late 20th century shaped the approach for the philosophy of pharmaceutical concern and the same had gradually moved into the developing countries in 21st century. The task of the pharmacists has progressed since that of a compounder and seller of medicinal products in the trend of that of a donor of care services and information and eventually that of a bringer of patient care. Cognitive pharmaceutical care includes a series of activities like medicine therapy management, health promotion and preventive care services to be specific and all these need to be performed in the safest and most effective way for the convenience of the patient. Pharmacists should carry on enlightening the community as regards their knowledge and central role as members of multidisciplinary health concern teams.

The present research has been undertaken with aim to evaluate in vitro drug release through egg membrane using keishary chein diffusion cell. So, the diffusion of diclofenac Sodium by the diclofenac Sodium gel was evaluated through egg membrane. In number of cases it may be advantageous to use animal skin as alternative for membranes as human skin. Due to physiological and morphological similarities between human skin and egg membrane the in vitro diffusion study was carried out by using egg membrane. In present work the marketed diclofenac gel was evaluated in vitro using egg membrane into Phosphate buffer at 37oC, where the sample was collected at timed intervals after initial spreading of gel on membrane and replaced with phosphate buffer to maintain sink condition and the concentration of diclofenac was assayed using U.V. Spectrophotometer at 276nm. From the study, it was concluded that marketed Diclofenac gel containing Diclofenac exhibited better drug release.

In present era, chromatography is the most important science of separation which is being used in all research centers, laboratories, agriculture, chemical, dyes and pharmaceutical industries of the world. Among all available chromatography techniques, High Performance Liquid Chromatography or HPLC is one of the widest and commonly used chromatographic techniques for analytical purpose. Recent improvement separation techniques and advancement in the instrumentation for liquid chromatography producing fast very efficient analytical separations. This article on chromatography will produces a short review of recent advancement in HPLC along with its principle and instrumentation. This study focus about recent emerging techniques in field of analytical chemistry, specifically chromatography.

At the end of December 2019, a completely unique coronavirus (COVID-19) caused a virulent disease in Wuhan, and has quickly spread to all provinces in China and 26 other countries around the world, leading to a heavy situation for epidemic prevention. Coronavirus pandemic is currently a world public health emergency. At the moment there's not any pharmacological treatment is thought to treat this condition, and there's a necessity to review the available treatments. Previous studies have shown that the role of Chloroquine and Hydroxychloroquine in various viral conditions, there's limited information about the utilization of them in COVID-19. The purpose of this systematic review is to summarize the available evidence regarding the role of chloroquine in the treatment of coronavirus infection. Here we found that treating the patients diagnosed as novel coronavirus pneumonia with chloroquine might improve the success rate of treatment, shorten hospital stay and improve patient outcome and hence pneumonia like symptoms can be treated. Conclusion: Considering minimal risk upon use, a protracted experience of use in other diseases, cost effectiveness and straightforward availability across India. We propose that both these drugs are deserve means last treatment, and may be carefully considered for clinical use as experimental drugs. Since HCQ has been approved for treatment of diabetes in India, it should be further research in COVID-19, a subgroup where significant mortality has been shown.