The deduction in the crop yield due to phytopathogenic fungi is increasing these years. Among which Mucor sp., causes a variety of diseases in crops. Although the botanical substances such as plant extract and essential oils impart high insecticidal and pesticidal activities, their application is not widespread due to its poor physicochemical properties. In order to overcome this problem, nano based synergistic essential oil (eucalyptus and oregano) technology has been deployed. In this study, a non-ionic surfactant was used to create a nanoemulsion from Eucalyptus globus and Origanum vulgare oil utilising a high energy emulsification technique. The Z-average diameter of the nanoemulsion droplets was discovered to be 19nm, and fluorescence microscopy imaging verified the spherical droplet shape of the nanoemulsion. When stored at room temperature (22°C), the nanoemulsion's size was shown to be physically stable for up to one month. The nanoemulsion's minimum inhibitory concentration (MIC) against Mucor sp. was 0.151mg/ml. Scanning electron microscopy and sodium dodecyl sulphate polyacrylamide gel electrophoresis were used to demonstrate how the nanoemulsion's ability to break the membrane of Mucor sp. The disease in chilli plants was significantly reduced by the use of synergistic nanoemulsion.
Raviswamy G. H. Math*, T. B. Suneetha, S. Jothi Prabha, Alifia C. Jafer, N. Preveena.
This study evaluated the Chemical investigation and assurance of a few mineral components of dry Moringa oleifera leaf and Capsules of Moringa oleifera leaf powder. The comes about appeared that the fiery debris, carbohydrate, fat, unrefined filaments, dampness and protein substance of dry Moringa oleifera were 0.95, 36, 15, 16.3, 12.1 and 25.1% separately. The Calcium (Ca), Iron (Fe), Zinc (Mg), Cadmium (Cd) and Lead (pb) substance were 80, 478, 810, 0.015 and 0.0006 parts per million (ppm), individually. Capsules of Moringa oleifera assessment were by and large comparable.
Hend Ismail*, Amna Alheddad, Hanan Milad, Asma M. Garged.
Theoretical calculation of (E)-5-((4-aminophenyl) diazenyl)-2-hydroxybenzaldehyde (1) and (E)-N-(4-((3-formyl-4-hydroxyphenyl) diazenyl) phenyl) acetamide (2) were studied by DFTB3LYP//6-311+G (d, p) basis set. The calculated values of geometric structural parameters, FT-IR spectral data, HOMO-LUMO, NBO, NISC, Fukui function, polarizability, hyperpolarizability and UV data of compounds 1 and 2 clearly indicate that substitution on amino group alters the physical properties of the compound 2. The NICS value of amino-substituted phenyl ring reduced the aromatic character due to lone pair electron on nitrogen involved inductive, conjunction and also OH, CHO, and NH2 and OH, CHO, and NHCOCH3 in compounds (1) and (2), respectively.
S. Richard Rajkumar, G. Rajarajan, V. Periyanayagasamy, V. Thanikachalam*.
Aquasomes are nanoparticles that are the most recently created drug delivery system and are ideal for the delivery of protein and peptides to overcome their limitations of chemical or physical instability, poor bioavailability typically caused by gastrointestinal enzymatic degradation and also the poor permeability of intestinal mucosa, through the oral route of administration. Aquasomes are novel rounded nanoparticulate drug carrier systems that vary in size from 60 to 300nm. They have a tri-layered structure with a solid core that provides structural stability for proteins and peptides, allowing for enough time for drug distribution in systemic circulation. These properties made the aquasomes as a prospective carrier system for the delivery of peptide based biopharmaceuticals and also designed for delivery of nanoparticulates like Anti-diabetic polypeptides such as- insulin and polypeptide-K, hemoglobin and various antigens, enzymes like serration peptidase via oral route.
Theoretical calculation of 4-((E)-(4-amino-phenyl)diazenyl)-2-((E)-(pyridin-2-ylimino) methyl) phenol (1) and N-(4-((E)-(4-hydroxy-3-((E)-(pyridin-2-ylimino)methyl)phenyl)diazenyl)phenyl)acetamide (2) were studied by DFT/B3LYP//6-311+G(d,p) basis set. The calculated values of geometric structural parameters, FT-IR spectral data, HOMO-LUMO, NBO, NISC, Fukui function, polarisability, hyperpolarisability and UV data of compounds 1 and 2 clearly indicate that substitution on amino group alters the physical properties of the compound 2. The NICS value of amino-substituted phenyl ring reduce the aromatic character due to lone pair electron on nitrogen involved in inductive, conjunction effect and also due to OH, NH2 and OH, NHCOCH3 in compounds 1 and 2, respectively. Solvent effect on different parameters were studied and found that increasing dielectric constant increases the studied parameter. The stability and planarity of the molecule’s effects on dipole moment, energy, polarisablity and hyperpolarisablity were studied vastly.
S. Richard Rajkumar, G. Vallal Perumal, G. Rajarajan, V. Periyanayagasamy, V. Thanikachalam*.